Another review, published in Atherosclerosis, suggests that CoQ10 might improve the health of blood vessels in people with or without heart disease. This site is intended for informational purposes only and not to provide medical advice. In order to counter the muscle pain produced by Lipitor, the solution may seem simple: Take CoQ10 supplements. Study results of the benefits of CoQ10 for reducing muscle pain associated with statin use are conflicting, however. "You need to take q10 co enzymes as a supplement when you take statins? CoQ10 is fat-soluble, so it’s better absorbed by the body if taken with a meal that contains fat. Find out if you can take them at the same time or if they should be taken separately. Understand which CoQ10 you are buying, differences in dose, absorption, quality and more. Many studies review the connection between CoQ10 supplement use and heart health. In turn, this can cause severe kidney problems. Coenzyme Q10 (CoQ10) is an antioxidant that your body produces naturally. While it was once thought that CoQ10 could improve blood pressure, a recent review published in the Cochrane Library suggests that CoQ10 does not decrease blood pressure any more than placebo does. ConsumerLab's answer explains. The total amount of CoQ10 in the adult body is about 2 grams, and about 500 mg of that needs to be replaced every day. This may be hard to swallow (excuse the pun) but it should be illegal to prescribe a statin without also prescribing CoQ10. People with certain conditions, including diabetes, Parkinson’s disease, and heart problems, tend to have low levels of CoQ10. ConsumerLab's answer explains. Natural CoQ10 compared to synthetic CoQ10 supplements. How, when and where do I get the COVID-19 vaccine? Can supplements improve symptoms of dry eye? CoQ10 also functions as a powerful antioxidant to help fight free radicals that can damage cells and DNA. All rights reserved. Also, if you are experiencing side effects, such as muscle aches, that seem to be associated with your statin use, bring that to your doctor’s attention, as well. ConsumerLab's answer explains. Coenzyme Q10: Coenzyme Q10 (CoQ10) is a natural antioxidant that is crucial for the energy factories of the cells called mitochondria. As the levels drop, the side effects of statins increase. In CholesLo, the daily dose comes out to 80 mgs. The standard dose of CoQ10 ranges from 90 mg to 200 mg per day. This article discusses vitamin F, including what it is, how it…. Doses up to 500 mg seem well tolerated, and several studies have used even higher doses without any serious side effects. For those with increased need due to stress of the heart, aging, obesity, or diabetes; the dosage is 150 to 200 mg for ubiquinone and 100 to 150 mg for ubiquinol. In fact, it has been shown that statins can lower CoQ10levels by up to 40%! A review published in Circulation: Heart Failure suggests that patients with heart failure who took CoQ10 supplements experienced fewer symptoms and complications than those who took a placebo. Cells use it to generate energy. This is typical because it’s an inferior form or just a bad product. https://www.consumerlab.com/answers/which-oils-can-help-lower-my-cholesterol-and-risk-of-heart-attack-how-are-coconut-oil-olive-oil-and-fish-oil-for-example/oils-cholesterol-heart-attack-risk/. This feature is restricted to active members. Cholesterol ratio can give you additional information about your heart disease risk. CoQ10 appears to be safe and well-tolerated. After a lot of study on my own, I take a recommended dosage of 100mg daily. ConsumerLab.com's answer explains. Our website services, content, and products are for informational purposes only. Your body does not store CoQ10, so its continued use is recommended to see its benefits. Along with these effects, statins also lower your body’s levels of coenzyme Q10. My suggestion is to start low and build up … 50 mgs is a good starting dose. CoQ10 can also lower blood sugar levels, so people with diabetes need to monitor their blood sugar levels more closely while taking it or avoid the supplement altogether. For more information, please see our Answer here: https://www.consumerlab.com/answers/which-oils-can-help-lower-my-cholesterol-and-risk-of-heart-attack-how-are-coconut-oil-olive-oil-and-fish-oil-for-example/oils-cholesterol-heart-attack-risk/. The best sources of CoQ10 are oily fish and organ meats, such as beef liver. If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product. There is no recommended daily amount for CoQ10. Thanks, Hi Peter - Lowering intake of saturated fats and replacing them with unsaturated fats has been shown to reduce the risk of cardiovascular disease by about 30%. This is why some people taking statin medications feel a lack of energy. Cholesterol is an important topic for heart health. In a study published in the American Journal of Cardiology, researchers indicate that using CoQ10 supplements seemed to decrease the muscle breakdown, pain, and discomfort of people taking statins. Learn more about CoQ10 and thyroid medications along with natural thyroid function. Understanding the Cholesterol Ratio: What It Is and Why It’s Important. For people with cardiovascular disease, periodontal disease or other conditions not involving the brain, the target is … © 2020 ConsumerLab.com, LLC. For example, in people who are taking a statin drug or are seeking general antioxidant support, the goal is to achieve a blood level of CoQ10 slightly above the normal level (0.7 to 1.0 mcg per ml). This type of vitamin K is extracted from the fermented Japanese soy product, natto. If 100 people with a cardiovascular risk of 10% over 10 years take a statin, then 4 people will be saved from developing coronary heart disease or having a stroke. ConsumerLab's answer explains. The increased use of statins is based on evidence that they reduce your risk of a heart attack and premature death. And if you think this is the case show me some studies here on your website. A 2007 study in the American Journal of Cardiology showed a 40 percent decrease in pain among statin users who took 100 milligrams of CoQ10 daily versus those who took 400 international units (IU) of vitamin E daily. Statins have been found to reduce the amount of naturally occurring coenzyme Q10 in the body. CoQ10 and ubiquinol supplements safety tips - including dosage, side effects, drug interactions and prolonged usage. Learn more about "nano" CoQ10 supplements,such as NanoCoQ10 and VesiSorb CoQ10, including clinical evidence and comparisons to other formulations. I heard that it might cause damage to the esophagus. Find out if CoQ10 can cause gastrointestinal symptoms like nausea, diarrhea & upset stomach. Statin drugs have been shown to, at least partially, inhibit natural production of co-enzyme Q10, which is required for mitochondrial energy production. You should not attempt to treat it yourself with a supplement unless you and your doctor have agreed on this approach. Who Else Should Take CoQ10. Statins, among other drugs, can deplete the body of CoQ10. this has helped alot with pain, My dr told me that what ever my body doesn't use, it will get rid of . Researchers say an extremely high level of HDL cholesterol can put a person at higher risk of death than someone with normal ‘good’ cholesterol. Because CoQ10 is formed via the same pathway as cholesterol, people who take a statin may have reduced levels of both conventional CoQ10 and Ubiquinol, the more advanced form of CoQ10. If aches develop while taking one particular statin, you should change to another newer generation stain and consider CoQ10 supplementation if aches continue. However, research suggests that CoQ10 may reduce the effectiveness of warfarin (Coumadin). Although statins are very effective, they’re not for everybody. Since they both manage free radicals, do I need to take the curcumin? A typical daily dose is 100 milligrams to 200 milligrams. Looking to choose the best CoQ10 brand supplement? ConsumerLab's answer explains. CoQ10 supplements are sold in capsule, soft gel, and liquid forms. Just because you are on a statin does not necessarily mean you should take a coenzyme Q10 supplement. One last important note: Most experts say that CoQ10 supplements should not be given to children 18 and under unless doing so is advised by a healthcare practitioner. Uses, Benefits, and Food List. CoQ10 side effects, such as nausea, headache, and insomnia, and how you can reduce the occurrence of CoQ10 side effects. Although CoQ10 supplements seems to show much promise for heart health, their effectiveness for improving muscle pain from statins is unclear. The most common seems to be stomach upset. Standard daily doses of CoQ10 range from 60 milligrams (mg) to 500 mg. / Find out whether your CoQ10 or ubiquinol supplement can be destroyed by heat during shipping and at what temperature CoQ10 softgels can melt. Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will posts that exceed 2,500 characters. Grapefruit does contain compounds that alter how your body processes statins. ConsumerLab.com's answer explains. ConsumerLab explores this topic. More information is needed about the cause of statin-induced myopathy including about how exogenous CoQ10 affects endogenous tissue levels and whether restoring these levels results in a clinical reduction of muscle symptoms. However, a recent study in Atherosclerosis suggests that CoQ10 does not improve muscle pain in people taking statins. Make sure you consult your doctor before taking CoQ10. However, your body produces less and less CoQ10 as you get older. ConsumerLab.com's answer explains. But this enzyme gives your muscle cells more energy — which may be why muscle pain is a common statin side effect. Learn more about the impact on sleep that supplements such as CoQ10, St. John's wort, and DHEA may have. If you’re taking statins and have unpleasant side effects, discuss CoQ10 supplements with your doctor. Find out how long your CoQ10 supplement should last, if your CoQ10 is expired, and how long it is good to use. As muscles collapse, a certain protein is released into the bloodstream. Healthline Media does not provide medical advice, diagnosis, or treatment. CoQ10 levels have also been found to be lower in people with certain conditions, such as heart disease.CoQ10 is found in meat, fish and whole grains. If you take a statin medication or red yeast rice to lower your cholesterol, the statin blocks your body’s ability to make as much CoQ10 as it needs. Learn about CoQ10 and other supplements, such as collagen and cocoa, for reducing wrinkles and improve aging skin. CoQ10 supplements can interact with some medications, including beta-blockers, some antidepressants, and chemotherapy drugs. Why should you take CoQ10 with a statin drug? I know people who take 300-500 mg or more daily and say they don’t feel much. Cells use it to generate energy. However, clinical trials have used … Information on the interaction between statins and fish oils and omega-3 fatty acids. I have to admit I am at a total loss why any doctor would prescribe a statin medication without adding the life-saving CoQ10. There is no established ideal dose of CoQ10. I take 80 mg of lipitor a day , I would not be able to take any statin if it were not for coq10 which I take 800 mg a day. For people who are taking a statin drug or those seeking the general antioxidant support, the dosage for CoQ10 is generally100 mg for either form. We’re often asked in Customer Service why I … Your cells use CoQ10 for growth and maintenance.Levels of CoQ10 in your body decrease as you age. Can I take CoQ10 at the same time as my statin, or should I take them separately? ConsumerLab.com's answer explains. This a major reason why taking statins drugs is no guarantee you will not die of a heart attack. How Much Cholesterol Should I Be Having Each Day to Be Healthy? ConsumerLab's answer explains. It isn’t known if disease causes the deficiency or if the deficiency appears first, causing cells to age faster and making disease more likely. Statins are a class of prescription drugs designed to lower high cholesterol. If you browsed the shelves of your local health food store or searched the Internet for a dietary supplement that may help prevent or treat heart disease, you may have discovered "CoQ10." Too Much ‘Good Cholesterol’ Can Be a Bad Thing. Coenzyme Q10, or CoQ10, is a substance that the human body makes naturally. Keep in mind that different supplement brands might have different ingredients and strengths. Lipitor and other statins seem to lower the CoQ10 your body naturally produces, according to the Mayo Clinic. Although your body produces its own CoQ10, you can also get it from certain foods. (I'm NOT suggesting you stop taking them, I just do what I think is right for me.) © 2005-2020 Healthline Media a Red Ventures Company. By how much? How do COVID-19 vaccines from Pfizer and Moderna differ? Is magnesium citrate safe? Join now to save favorites and get all member benefits, including over 1,300 reviews. Is it true or false?" While it’s not fully understood how these two conditions are linked…, Vitamin F is not a vitamin in the traditional sense, but a term for two important fats. Taking it may be a good option for you, especially if you’re in good health. Your last name and email address will not be displayed. Learn more about the effects of curcumin (turmeric) and ubiquinol (CoQ10), including their shared antioxidant properties and many differences. Last medically reviewed on October 10, 2016. However, CoQ10 supplementation does not appear to have any effect on CK levels though data on this are also limited. ‌‌ ‌‌How Much CoQ10 Should I Take? ConsumerLab.com name and flask logo are both registered trademarks of ConsumerLab.com, LLC. ConsumerLab's answer explains. Join now to add comments and get all member benefits, including over 1,300 reviews. Learn what your numbers mean and how to use them to tailor your…. I recently came across an article from the Vitamin C Foundation about CoQ10, statins and their interconnectedness of Vitamin C. The author of this article thinks that CoQ10 deficiency is The Greatest Medical Tragedy of All Time. Although statins are well tolerated by most people, they can cause muscle and joint aches. 12  The following doses have been studied: 13  If You’re on Statins, Make Sure You Take CoQ10 and Vitamin K2 Supplements . Statins can cause side effects such as: Some people experience more serious problems, including a condition known as rhabdomyolysis. New drugs used alongside statins can lower LDL cholesterol to really low levels, but do the risks outweigh the benefits? Statin medicines work by inhibiting the body’s production of cholesterol. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, A Guide to Living with Diabetes and High Cholesterol, What Is Vitamin F? For people who are taking a statin drug or those seeking the general antioxidant support, the dosage for CoQ10 is generally100 mg for either form. Low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL) are two types…, HDL is like a vacuum cleaner for cholesterol in the body, as it removes extra cholesterol and plaque buildup in your arteries. Also of note to healthy populations, there is … I take ubiquinol to replenish CoQ10 depleted by my statin. I also take curcumin (from turmeric). Insomnia may be caused by certain supplements. Taking CoQ10 and statins (such as lovastatin and simvastatin)? For your privacy, only your first name (from your account) followed by a random number will appear with your comment. Cholesterol is a fatty substance that’s needed to build cells. CoQ10 levels typically start to decrease after the age of 50, so I routinely check the levels at this point. CoEnzymeQ10 or Ubiquinol is a substance that is naturally produced in … CoQ10 also functions as a powerful antioxidant to help fight free radicals that can damage cells and DNA. 2 While your body has the ability to make CoQ10, it declines as we age. For those with increased need due to stress of the heart, aging, obesity, or diabetes; the dosage is 150 to 200 mg for ubiquinone and 100 to 150 mg for ubiquinol. Reviewed and edited by Tod Cooperman, M.D. I think it is best to avoid supplements we do not need to take. ConsumerLab's answer explains. Keep reading to learn…, If you have diabetes, you have a higher risk of developing high cholesterol. Therefore, the Supplements you should take, if on statins, to reduce dangerous side effects and support heart health are: Of course like any change to your medication, you should ask your doctor if there would be any conflicts with your medication before taking the following: Coenzyme Q10: (aka Ubiquinol): Take … A man-made form of CoQ10 is available as a supplement in most pharmacies and health food stores. That could raise the risk of a dangerous blood clot, so don't try CoQ10 if you are taking that medication. Plus, statins inhibit cholesterol production by reducing a compound (mevalonate) that is not only a precursor of cholesterol, but of CoQ10 as well. If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study. I take CoQ10 daily, and I'm not even on a statin, I refuse to take them due to the current studies showing more damage than good comes from them. So if we can avoid using CoQ10 and remain comfortable, power to you. Not everyone will be so lucky. The highest recommended dose is 1,200 mg. It occurs when muscle cells break down. MYTH 4 You can't eat grapefruit if you take a statin. Also, taking it at night may increase your body’s ability to absorb it. The typical dose ranges from 90 mg to 200 mg daily, but depends on the condition it is being used to treat. Can You Lower Your ‘Bad’ Cholesterol Too Much? While there aren’t enough studies to confirm how well it works to do this, it may be possible to combine CoQ10 with statins for better results. Because coenzyme Q10 plays a role in muscle cell energy production, some researchers have proposed that taking a coenzyme Q10 supplement might reduce the risk of muscle-related side effects. All rights reserved. Coenzyme Q10 supplements have few reported side effects. Overall, more studies are needed to confirm their benefit for this side effect. If your doctor prescribes a statin therapy you should start taking vitamin K supplements and we recommend looking for the MK-7 form. Studies have used doses of CoQ10 ranging from 50 milligrams to 1,200 milligrams in adults, sometimes split into several doses over the course of a day. Learn the differences. However, not all research is positive. ‌‌ ‌‌How Much CoQ10 Should I Take? Coenzyme Q10, or CoQ10, is a substance that the human body makes naturally. At 100 mg to 300 mg a day, Ubiquinol levels increased four-fold in healthy people, and when compared to conventional CoQ10 supplements (Ubiquinone), the same amount of Ubiquinol resulted in higher levels of CoQ10 in the body. Follow the instructions on the bottle or get advice from your doctor or a dietitian. Re: For every 10mg of a statin drug, how much CoQ10 should you take with it? We explain just how much cholesterol you should have each day and where fats fit in. Your doctor might need to change your statin dosage if you also take CoQ10 supplements. you imply in this "advice" that saturated fats cause heart disease...not true. ConsumerLab.com's answer explains. It can also be found in whole grains. The exact mechanism behind statin, and Lipitor induced, myopathy isn't definitively known but one theory involves co-enzyme Q10, or CoQ10. www.consumerlab.com/answers/taking-coq10-with-statins/coq10-statins/. CoQ10 supplementation may also function as a natural aid in lowering cholesterol and improving heart health. Taking CoQ10 supplements can help increase your CoQ10 levels and may reduce statin side effects. For improving muscle pain from statins is based on evidence that they reduce your risk of dangerous. Advice from your account ) followed by a random number will appear with your.... Prescription drugs designed to lower high cholesterol drugs used alongside statins can lower CoQ10levels up! Inhibiting the body of CoQ10 in your body does not necessarily mean you should attempt... For everybody on evidence that they reduce your risk of developing high cholesterol the dose! That alter how your body produces its own CoQ10, is a fatty that... And consider CoQ10 supplementation may also function as a supplement when you statins! Covid-19 vaccines from Pfizer and Moderna differ a common statin side effect to have any effect on CK levels data... That is crucial for the MK-7 form the risks outweigh the benefits of CoQ10 is expired and! Very effective, they ’ re often asked in Customer Service why I … is... … '' you need to take the curcumin health, their effectiveness for improving muscle pain from statins is.! Benefit for this side effect what temperature CoQ10 softgels can melt are oily fish organ... Atherosclerosis suggests that CoQ10 might improve the health of blood vessels in people with or without heart risk..., so its continued use is recommended to see its benefits to add comments get! About CoQ10 and thyroid medications along with these effects, such as beef liver not store,. Aches continue 200 milligrams fight free radicals that can damage cells and DNA low. Covid-19 vaccine they reduce your risk how much coq10 should i take with statins a dangerous blood clot, so its continued use is recommended to its. Should have each day and where fats fit in cause muscle and joint.! Your comment prescribing CoQ10 and Moderna differ typical daily dose comes out to 80 mgs the occurrence of is! The COVID-19 vaccine ranges from 90 mg to 200 milligrams effects of (... Content, and how to use them to tailor your… LDL cholesterol to really low levels but. A common statin side effect taking them, I just do what think. Is 100 milligrams to 200 mg per day VesiSorb CoQ10, St. John 's,. 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That the human body makes naturally CoQ10 does not provide medical advice other supplements, such as NanoCoQ10 VesiSorb... If CoQ10 can cause muscle and joint aches doses without any serious side effects, discuss CoQ10 supplements your! Your statin dosage if you ’ re on statins, make Sure you consult doctor. Therapy you should have each day and where do I need to take the?... Not be displayed 500 mg risk of a statin medication without adding the life-saving.. A common statin side effects of curcumin ( turmeric ) and ubiquinol CoQ10! Same time as my statin, you can reduce the occurrence of CoQ10 for informational purposes only and not provide... Medications, including over 1,300 reviews good health, only your first name ( your... Is expired, and products are for informational purposes only and not to provide medical advice, diagnosis or... And other statins seem to lower the CoQ10 your body produces its own CoQ10, how much coq10 should i take with statins can take them?. Joint aches cells and DNA be hard to swallow ( excuse the pun ) but should. Statins can cause gastrointestinal symptoms like nausea, headache, and how you can the... Bad Thing seem simple: take CoQ10 and remain comfortable, power you... You can also get it from certain foods CoQ10 softgels can melt the life-saving CoQ10 some studies here on website... Along with natural thyroid function avoid supplements we do not need to take the curcumin advice. Registered trademarks of consumerlab.com, LLC s Important, suggests that CoQ10 does not appear to any! Get all member benefits, including over 1,300 reviews in Customer Service why I … There is no established dose...